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Clinical Trials of Aeknil Injection by
DR.S.N LOHE, M.D, D.C.H & DR.P.R DESHPANDE, M.D, D.C.H


 

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MODE OF ADMINISTRATION 

 

 ORAL

I.M INJECTION

TOTAL

 AEKNIL

 27

 93

 120

 A.P.C

 120

 --

120

 MIST. DIAPHORETIC

 120

 --

 120

AEKNIL was administered intramuscularly whenever it was found difficult to give it orally e.g., in severe vomiting, physical inability to swallow due to various causes, when child refuses to feed and when malabsorption was suspected. 

Response to the treatment was judged as: 

Good:

When temperature subsided completely or was reduced by at least 3°F. within 12 to 24 hours of administering the drug.

Fair:

When temperature was reduced by at least 2°F. within 24 to 48 hours of Administering the drug.

Poor:

When there was no reduction in pyrexia after 48 hours treatment. 

The antipyretic was administered for 2 to 5 days. Results are tabulated below:

  

 Good

 Fair

 Poor

 Total

 AEKNIL

 48

 60

 12

 120

 A.P.C

 44

 53

 23

 120

 MIST. DIAPHORETIC

 25

 61

 34

 120

The pyrexia ranged from 99° F. to 106° F. AEKNIL was found to be of considerable value in controlling pyrexia in U.R.T.I, Bronchiolitis, Bronchopneumonia, Meningitis, Febrile and some cases of P.U.O.

The response was poor in the miscellaneous group.

 

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