TABLE 2
AVERAGE SERUM CONCENTRATION AT EACH
SAMPLING TIM
HOUR
|
Average Serum Concentration
(mg/ml) |
T-TEST |
|
|
STANDARD |
TEST
AEKNIL 150 mg/ml
|
|
|
0 |
|
0 |
|
|
0 |
|
0.036 |
|
|
0.25 |
|
1.494 |
|
|
0.5 |
|
0.535 |
|
|
1.0 |
|
0.311 |
|
|
2.0 |
|
0.281 |
|
|
4.0 |
|
0.203 |
|
|
6.0 |
|
0.055 |
|
|
8.0 |
|
0.010 |
|
TABLE
3
PARAMETERS OF BIOAVAILABILITY
|
|
STANDARD |
TEST
AEKNIL 150 mg/ml |
VARIANCE % |
|
G (mg + S.E.M)
Max |
|
1.494 + 0.374 |
|
|
T (hr + S.E.M)
Max
|
|
0.25 + 0.025 |
|
|
AUC (mg/8 hr) |
|
1.76 |
|
|
